Applications
Cornel Medical works with leading specialists and researchers to bring the benefits of continuous automated real-time monitoring of biomarkers into practice using the MicroEye® and ContinuMon® This revolutionary technology can be used for a number of applications including but not limited to; glucose monitoring and glucose tolerance testing, lactate monitoring and threshold testing, poor tissue perfusion, therapeutic monitoring of antibiotics, immunosuppressants, anaesthesia agents, and others.
Improving Anaesthesia
Real time monitoring of Propofol
Using the MicroEye®, Somnus Scientific have developed real-time blood propofol concentration monitor that provides a continuous measurement of propofol in the patient’s blood without the need for blood sampling or withdrawal.
This is achieved with an analyte recovery system inserted into an intravenous cannula that passes a dialysate containing the analyte (propofol) over our unique biosensor.
The measured concentration of propofol can then be displayed or fed to a variety of instruments or monitors.
What can I monitor?
Lactate
Lactate
Propofol
Propofol
Immuno-suppressants
Immuno-suppressants
Antibiotics
Antibiotics
Latest clinical studies
Immunosuppressant quantification in intravenous microdialysate
Therapeutic drug monitoring (TDM) plays a crucial role in personalized medicine. It helps clinicians to tailor drug dosage for optimized therapy through understanding the underlying complex pharmacokinetics and pharmacodynamics. Conventional, non-continuous TDM fails to provide real-time information, which is particularly important for the initial phase of immunosuppressant therapy, e.g., with cyclosporine (CsA) and mycophenolic acid (MPA).
Application of optical sensing in POCT
Cornel’s MicroEye(R) microdialysis device is a key factor in enabling therapeutic drug monitoring of immunosuppressants drugs to prevent rejection in transplant patients.
Real-time continuous monitoring of antibiotics in critically ill patients
Cornel Medical is leading specialist teams from University College London and the Institute for Bio-Sensing Technology (IBST) at the University of the West of England to develop technology to provide real-time continuous monitoring of antibiotics in critically ill patients.